What is Celecoxib?
Celebrex (cele-koh-KOW-sis) is a nonsteroidal antiinflammatory drug (NSAID). It was developed by Merck & Co. Inc., a pharmaceutical company based in West Point, Pennsylvania. It was approved by the FDA in 2001 and became available worldwide in 2002.
The main active ingredient of celecoxib is called cobicistat. It is a synthetic analogue of the natural substance known as ciclosporin. Citicocosporin is a type of protein that protects the body from infection. It also helps the body increase its ability to heal after an injury.
Celecoxib is in a group of drugs called cyclooxygenase-2 (COX-2) inhibitors. The COX-2 enzyme is responsible for the formation of inflammatory prostaglandins. Prostaglandins are hormone-like substances that promote pain, fever, and inflammation.
Nonsteroidal anti-inflammatory drugs (NSAIDs) like celecoxib work by reducing the levels of prostaglandins. This reduces pain, swelling, and fever. It also reduces the sensitivity of the pain receptors.
The Food and Drug Administration (FDA) approved this drug in May 2001 as a pain reliever and anti-inflammatory drug. It was introduced in the United States as Celebrex.
In the United Kingdom, it is referred to as celecoxib. In Australia, it is referred to as Celebra. It is also known as Celebrex in South Africa and Mexico.
The drug’s manufacturer, Merck & Co. Inc., has also applied for approval of the drug in Canada, the European Union (EU), and Switzerland. The drug became available in most of these locations in the year 2002.
The drug company Pfizer manufactures a generic version of the drug in both capsule and tablet form.
Celebrex is one of Merck’s best-selling drugs. In 2008, sales of the drug were $2.1 billion in the United States, and $4.2 billion worldwide.
The drug was Merck’s top-selling product by 2009. It has been available as a generic since 2013.
In the United States, the wholesale cost of a one-month supply of celecoxib is between $20 and $45. In Malaysia, the price is around US$1.
Celebrex is used to treat the same medical conditions as ibuprofen, another popular NSAID. It is used to treat pain caused by arthritis, osteoarthritis, menstrual pain, and muscle pain. It can also be used to reduce fever. It can be used on the same conditions as naproxen, another NSAID.
It may also be used to treat conditions that cause inflammation and pain. These include gout, bursitis, tendonitis, and fibromyalgia.
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