Polycystic Kidney Disease (PKD) is a genetic disorder characterized by multiple cysts or small tumors in the kidneys. The most common type of PKD is known as primary sclerosing cholangitis (PSC). Other types include idiopathic, acquired, and environmental.
What are the symptoms of Polycystic Kidney Disease?
The signs and symptoms of PSC may not appear until the disease is in an advanced stage, resulting in kidney failure. The most common sign is the inability to pass urine. Other signs and symptoms may include
• Swelling of the abdomen due to buildup of fluid
• Loss of appetite
Who gets Polycystic Kidney Disease?
The exact cause of primary sclerosing cholangitis (PSC) is unknown. It may be caused by an infectious agent or secondary to other diseases. The disease is more common in men than in women.
What are the risk factors for Polycystic Kidney Disease?
The following are risk factors for PSC:
• Age. PSC affects men more often than women and most cases occur in people over the age of 40.
Sources & references used in this article:
- Chromosome 4 localization of a second gene for autosomal dominant polycystic kidney disease (DJM Peters, L Spruit, JJ Saris, D Ravine, LA Sandkuijl… – Nature …, 1993 – nature.com)
- Increased incidence of gastrointestinal surgical complications in renal transplant recipients with polycystic kidney disease1 (KA Andreoni, RP Pelletier, EA Elkhammas… – …, 1999 – journals.lww.com)
- Adult dominant polycystic kidney disease–clinical problems (M Zeier, S Geberth, E Ritz, T Jaeger, R Waldherr – Nephron, 1988 – karger.com)
- Chronic kidney disease in Southwestern Iranian children (A Ahmadzadeh, E Valavi, KM ZANGENEH… – 2009 – sid.ir)
- Current concepts and controversies in imaging of renal cystic diseases (E Levine, DS Hartman, JW Meilstrup… – Urologic Clinics of North …, 1997 – Elsevier)
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