What is Urethritis?
Urethritis (UR) is a common autoimmune disease characterized by inflammation of the joints. The immune system mistakenly attacks healthy cells in your body such as cartilage, ligaments, tendons, bone marrow and blood vessels. These abnormal cells are called “autoantigens.” This inflammatory response causes pain and swelling which may last from days to years. The most common symptoms include:
Pain in the affected joint(s). Pain is usually felt on one side of the joint and may radiate to other parts of your body. You may have numbness or tingling in this area.
Joint stiffness/stiffness. Joint stiffness may cause you to lose balance, especially when walking or climbing stairs. Your leg muscles will not work properly, causing weakness and fatigue.
Swelling of the affected joint(s). Swelling may occur in other areas of your body, particularly around your ankles and feet.
Tenderness over the affected joint(s). Tenderness over the affected joint(s) may result in swelling of the skin and surrounding tissues. This condition is known as edema. If left untreated, it can lead to death due to infection or secondary complications.
What causes Urethritis?
Urethritis is caused by an autoimmune disorder in which the body attacks its own healthy cells. Urethritis can be triggered by certain illnesses, such as:
Human Immunodeficiency Virus (HIV)
Hepatitis C and B
Other viruses and diseases may also cause urethritis.
Who is at risk for Urethritis?
Men in their 30s and 40s are more likely to develop Urethritis because of:
Exposure to an illness or virus.
Sexual activity with multiple partners. (This increases your chance of being exposed to a virus or disease.)
Use of injection drugs.
What are the common causes of Urethritis?
Most types of Urethritis are considered sexually transmitted diseases (STDs).
- Etiology of nongonococcal urethritis (KK Holmes, HH Handsfield, SP Wang… – New England journal …, 1975 – Mass Medical Soc)
- Azithromycin failure in Mycoplasma genitalium urethritis (CS Bradshaw, JS Jensen, SN Tabrizi… – Emerging infectious …, 2006 – ncbi.nlm.nih.gov)
- Mycoplasma genitalium: a cause of male urethritis? (JS Jensen, R Orsum, B Dohn, S Uldum… – Sexually Transmitted …, 1993 – sti.bmj.com)
- Association of Mycoplasma genitalium with acute non-gonococcal urethritis (PJ Horner, CB Gilroy, BJ Thomas, D Taylor-Robinson… – The Lancet, 1993 – Elsevier)
- Mucopurulent cervicitis—the ignored counterpart in women of urethritis in men (RC Brunham, J Paavonen, CE Stevens… – New England journal …, 1984 – Mass Medical Soc)
- Diagnosis and etiology of nongonococcal urethritis (SL Swartz, SJ Kraus, KL Herrmann… – Journal of Infectious …, 1978 – academic.oup.com)
- Association of Ureaplasma urealyticum (biovar 2) with nongonococcal urethritis (T Deguchi, T Yoshida, T Miyazawa… – Sexually transmitted …, 2004 – journals.lww.com)